ACZONE® (dapsone) Gel 5%
The ACZONE® Gel Experience - Get acne relief

ACZONE® (dapsone) Gel 5% is a prescription medicine to treat acne. It’s simple to apply the lightweight gel. And it’s a medication that’s proven effective.


The ACZONE® Gel Experience

How does ACZONE® Gel fit into my daily schedule?

Twice a day is all it takes to get you on your way to clearer skin. Gently wash your face and apply the lightweight ACZONE® Gel. You can wear it under your makeup. It’s easy to apply.

When will I see results?

Clinical research shows that, when used as directed, results are seen as early as 12 weeks.1 Your results may vary.

Can I use ACZONE® Gel with makeup?

You should always apply ACZONE® Gel before you put on any makeup or other skin products. While your first impulse may be to cover up your acne, heavy foundations can often clog pores and exacerbate the problem. Look for oil-free and non-comedogenic makeup products.

What about sunscreen or moisturizers?

You can use sunscreen and moisturizers with ACZONE® Gel, though you should seek out products that are non-comedogenic (ones that don’t clog your pores). Remember that overexposure to sunlight can damage unprotected skin–you should always wear sunscreen!

What if I'm physically active? Do I need to re-apply after workouts?

ACZONE® Gel is indicated for twice-daily use. If applied correctly, you should not need any additional applications. As everyone’s skin type is different, you should consult with your dermatologist regarding the best treatment course for your individual needs and lifestyle.

How long do I need to stay on my medication?

You should discuss the length of your treatment with your dermatologist. Your doctor can help you achieve results.


For most insured patients. This program is not
valid for prescriptions reimbursed under Medicare, Medicaid, or any other federal or state program or where prohibited by law.

Ask Your Dermatologist
Talk to your dermatologist about ACZONE® Gel. If you don't have a dermatologist, we can help you find one.

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Share Your Acne Story
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ACZONE® experience.

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ACZONE® Gel is a prescription medicine used on your skin (topical) to treat acne in people 12 years and older.


Do not use ACZONE® Gel if you are allergic to any of the ingredients in ACZONE® Gel or if you are younger than 12 years of age.

Tell your doctor about all of your medical conditions, including if you have glucose-6-phosphate dehydrogenase deficiency (G6PD) which may put you at a greater risk for developing a low red blood cell count. If you experience signs and symptoms such as back pain, breathlessness, tiredness/weakness with daily activities, dark-brown urine, high fever, and yellow or pale skin, stop use and call your doctor immediately.

The most common side effects of ACZONE® Gel are dryness, redness, oiliness, and peeling of the skin being treated.

Talk to your doctor about any medications you’re using including topical benzoyl peroxide (BPO). Use of BPO with ACZONE® Gel may cause your skin to temporarily turn yellow or orange at the site of application.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Click here for full Prescribing Information and the Patient Labeling

  1. Draelos ZD, Carter E, Maloney JM, et al; for United States/Canada Dapsone Gel Study Group. Two randomized studies demonstrate the efficacy and safety of dapsone gel, 5% for the treatment of acne vulgaris. J Am Acad Dermatol. 2007;56(3):439.e1-439.e10.