ACZONE® (dapsone) Gel 5%
The ACZONE® Gel Experience - Get acne relief

ACZONE® (dapsone) Gel 5% is a prescription medicine to treat acne. It’s simple to apply the lightweight gel. And it’s a medication that’s proven effective.


The ACZONE® Gel Experience

How does ACZONE® Gel fit into my daily schedule?

Twice a day is all it takes to get you on your way to clearer skin. Gently wash your face and apply the lightweight ACZONE® Gel. It’s easy to apply.

When will I see results?

Clinical research shows that, when used as directed, results are seen as early as 12 weeks.1 Your results may vary.

What if I'm physically active? Do I need to re-apply after workouts?

ACZONE® Gel is indicated for twice-daily use. If applied correctly, you should not need any additional applications. As everyone’s skin type is different, you should consult with your dermatologist regarding the best treatment course for your individual needs and lifestyle.

How long do I need to stay on my medication?

You should discuss the length of your treatment with your dermatologist. Your doctor can help you achieve results.


For most insured patients. This program is not
valid for prescriptions reimbursed under Medicare, Medicaid, or any other federal or state program or where prohibited by law.

Ask Your Dermatologist
Talk to your dermatologist about ACZONE® Gel. If you don't have a dermatologist, we can help you find one.

Share Your Success
Share Your Acne Story
Tell us your story and share your own
ACZONE® experience.

Share My Success Story


ACZONE® Gel is a prescription medicine used on your skin (topical) to treat acne in people 12 years and older.


Do not use ACZONE® Gel if you are allergic to any of the ingredients in ACZONE® Gel or if you are younger than 12 years of age.

Tell your doctor about all of your medical conditions, including if you have glucose-6-phosphate dehydrogenase deficiency (G6PD) which may put you at a greater risk for developing a low red blood cell count. If you experience signs and symptoms such as back pain, breathlessness, tiredness/weakness with daily activities, dark-brown urine, high fever, and yellow or pale skin, stop use and call your doctor immediately.

The most common side effects of ACZONE® Gel are dryness, redness, oiliness, and peeling of the skin being treated.

Talk to your doctor about any medications you’re using including topical benzoyl peroxide (BPO). Use of BPO with ACZONE® Gel may cause your skin to temporarily turn yellow or orange at the site of application.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Click here for full Prescribing Information and the Patient Labeling

  1. Draelos ZD, Carter E, Maloney JM, et al; for United States/Canada Dapsone Gel Study Group. Two randomized studies demonstrate the efficacy and safety of dapsone gel, 5% for the treatment of acne vulgaris. J Am Acad Dermatol. 2007;56(3):439.e1-439.e10.